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Department of Cell and
          Molecular Biology, Chemical biology Programme

Doctoral Dissertations in Bioorganic Chemistry/Chemical Biology

Supervised by Prof. Jyoti Chattopadhyaya

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Present affiliations are shown in Green

2014
32.
Novel Pentofuranose Chemistry to Modulate RNA Function
Mansoureh Karimiahmadabadi
Department: Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology, Chemical Biology Publication type: Doctoral thesis, comprehensive summary (Other academic) Language: English Place of publ.: Uppsala Publisher: Acta Universitatis Upsaliensis, Series: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, SSN 1651-6214 ISBN 978-91-554-9069-0 Permanent link: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-233898

The Ph.D. dissertation presented at Uppsala University has been publicly examined on November 28 2014 in A1:104b located at Biomedical Centre (BMC), Uppsala University ,  Husargatan 3, Uppsala. Faculty opponent: Professor Jesper Wengel (Department of Physics, Chemistry and Pharmacy, University of Southern Denmark)

2012
31. Conformationally Constrained Oligonucleotides for RNA Targeting
Li Qing
Department: Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology, Chemical Biology Publication type: Doctoral thesis, comprehensive summary (Other academic) Language: English Place of publ.: Uppsala Publisher: Acta Universitatis Upsaliensis Pages: 66 Series: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214; 948 Year of publ.: 2012 URI: urn:nbn:se:uu:diva-179069 Permanent link: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179069 ISBN: 978-91-554-8414-9

The Ph.D. dissertation took place on September 22, 2012, Room B7:101a:301, Husargatan 3, Biomedical Center, Uppsala University, Uppsala.
Opponent: Zhang, Li-He (Peking University, State Key Laboratories of Natural and Biomimetic drugs)

Click on the highlighted links to download: 

Present affiliation:

2010
30. Conformationally Constrained Nucleic Acids as Potential RNA Targeting Therapeutics.
Zhou Chuanzheng.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology,  ISSN 1651-6214; ISBN 978-91-554-7728-8; http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-114136

The Ph.D. dissertation took place at 14:00 on March 31, 2010, Room C10:301 (floor 3), Husargatan 3, Biomedical Center, Uppsala University, Uppsala.
Opponent: Professor Serge L. Beaucage, NIH/Bethesda, Center for Biologics Evaluation and Research, FDA, Bethesda, MD

Click on the highlighted links to download: 
Annoucement, Paper I, Paper II, Paper III, Paper IV, Paper V, Paper VI, Paper VII, Paper VIII

Present affiliation: Postdoc, Department of Chemistry, The Johns Hopkins University, Baltimore, MD 21218

2008

29. Conformationally Constrained Nucleosides, Nucleotides and Oligonucleotides. Design, Synthesis and Properties.
Dmytro Honcharenko.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214 ; ISBN 978-91-554-7219-1.
The Ph.D. dissertation took place on June 5, 2008 at the Biomedical Center, Uppsala University, Uppsala.
Opponent: Herdewijn, Piet, Professor, Dr, Department of Pharmaceutical Sciences, Lab. Medicinale chemie, Leuven, Belgium.
University posting page

Click on the highlighted links to download: 
Annoucement, Paper I, Paper II, Paper III, Paper IV, Paper V, Paper VI.

Present affiliation: Postdoc, Karolinska Institutet, Department of Biosciences and Nutrition

2006
28. Some Aspects of Physicochemical Properties of DNA and RNA. .
Sandipta Acharya.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214 ; ISBN 91-554-6518-8.
The Ph.D. Dissertation took place April 29, 2006 at the Biomedical Center, Uppsala University, Uppsala.
Opponent: Herdewijn, Piet, Professor, Dr, Department of Pharmaceutical Sciences, Lab. Medicinale chemie, Leuven, Belgium.
University posting page
Click on the highlighted links to download: 
Annoucement, Paper I, Paper II, Paper III, Paper IV, Paper V Paper VI Paper VII Paper VII Paper IX

Present affiliation: Research Associate, University of Alberta, Alberta, Canada



2005
27. Studies on Nucleic Acids - Structure and Dynamics
Johan Isaksson.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214, ISBN 91-554-6293-6
The Ph.D. Dissertation took place on September 16, 2005 at BMC, Uppsala University.
University posting page
Click on the highlighted links to download: 
Paper I, Paper II, Paper III, Paper IV, Paper V, Paper VI

Present affiliation: Research Scientist, Medivir AB, Huddinge, Stockholm



2004
26. Chemically Modified Oligonucleotides: Synthesis, Physicochemical and Biochemical Properties of their Duplexes with DNA and RNA
P.I. Pradeepkumar.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1104-232X, ISBN 91-554-5957-9
The Ph.D. Dissertation took place on May 21, 2004 at BMC, Uppsala University.
University posting page
Click on the highlighted links to download: 
Paper I, Paper II, Paper III, Paper IV, Paper V, Paper VI (submitted), Paper VII (submitted), Paper VIII, Paper IX.

Present affiliation: Assistant Professor of Chemistry, Indian Institute of Technology, Bombay



2003
25. Studies on the Non-covalent Interactions (Stereoelectronics, Stacking and Hydrogen Bonding) in the Self-assembly of DNA and RNA .
Parag Acharya.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1104-232X, ISBN 91-554-5821-1
University posting page
Click on the highlighted links to download: 
Paper I, Paper II, Paper III, Paper IV, Paper V, Paper VI, Paper VII, Paper VIII, Paper IX (submitted), Paper X .

Present affiliation: Senior Biochemist at Picomole Instruments Inc.



2002
24. Aspects of Antisense and Antigene of Oligonucleotides Tethered to Intercallators.
Dimitri Ossipov.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISBN 91-554-5365-1
Click on the highlighted links to download Annoucement, Paper I, Paper II, Paper III, Paper IV, Paper V.

Present affiliation: Assistant Professor (Forskarassistent),  Department of Materials Chemistry, Polymer Chemistry, Uppsala University


2000

23. Some Aspects of Nucleic Acid Chemistry
Edouard Zamaratski.
ISSN 1104-232X, ISBN 91-554-4868-2
Click on the highlighted links to download: 
Paper I, Paper II, Paper III, Paper IV, Paper V, Paper VI, Paper VII, Paper VIII

Present affiliation: Senior Sceintist, Group Leader, Karabio AB, Stockholm



1999

22. Stereoelectronic Effects in Nucleosides and Nucleotides
Christophe Thibaudeau.
ISBN 91-554-4365-6

Present affiliation: Researcher at National Center for Scientific Research at University of Nantes, France

21. Studies on Nucleic Acids Chemistry.
Nitin Puri. ISBN 91-554-4348-6

Present affiliation: Senior Manager, Nucleic Acid Chemistry & Delivery, Life Technologies



1996

20. Synthetic and Structural (NMR) Studies on DNA and RNA.
Shun-Ichi Yamakage.
ISBN 91-554-3821-0

Present affiliation: Research Director, RIKEN Genomic Sciences Center, Hyogo, Japan



1995

19. Studies on Stereoelectronic Effects in Nucleosides and Nucleotides.
Janez Plavec. ISBN 91-554-3553-X

Present affiliation: Professor, Head of NMR center at National Institute of Chemistry, Ljubljana, Slovenia



1994

18. Some Recent Developments in Nucleoside Chemistry.
Nafizal Hossain. ISBN 91-554-3346-4

Present affiliation: Research Director, Astra Zeneca AB

17. Some New Aspects of Nucleoside Chemistry.
Zhen Xi. ISBN 91-554-3292-1

Present affiliation: Professor of college of life Science, Nankai University



1993

16. Conformational Analysis of Ribonucleic acids (RNA) by NMR Spectroscopy.
Peter Agback. ISBN 91-554-3127-5

Present affiliation: Research Director, NMR Lab, Karabio AB, Stockholm

15. Studies on Nucleic Acid Chemistry.
András Földesi. ISBN 91-554-3075-9

Present affiliation: Senior Research Engineer, Bioorganic Chemistry, UU, Uppsala

14. Studies on Nucleoside Chemistry.
Weimin Tong. ISBN 91-554-3048-1

Present affiliation: Vice President R&D, Beijing Honghui Meditech Co., Ltd



1992

13. Studies on Ribonucleic Acid (RNA) Chemistry.
Christian Sund. ISBN 91-554-2984-X

Present affiliation: Associate Research Director, Medivir AB, Stockholm



1991

12. Structural Studies on Nucleosides and Nucleotides by Nuclear Magnetic Resonance (NMR) Spectroscopy.
Corine Glemarec. ISBN 91-554-2803-7

Present affiliation: Professor, SLU, Uppsala



1990

11. Studies on Nucleoside Chemistry.
Jin-Chang Wu. ISBN 91-554 -2655-7

Present affiliation: Professor, The Center for Combinatorial Chemistry and Drug Discovery, Jilin University, 75 Jinlai St., Changchun



1989

10. Synthesis, Separation, and Structure of Ribonucleic Acids and a Toxic Cyclic Peptide.
Anders Sandström. ISBN 91-554-2476-7

Present affiliation: Associate professor, Lecturer in organic chemistry, Director of Graduate Studies, SLU, Uppsala

9. Studies on Nucleoside and Nucleotide Chemistry.
Jean-Marc Vial. ISBN 91-554-2450-3

Deceased



1988

8. Studies on Nucleic Acid Chemistry.
Xiao-Xiong Zhou. ISBN 91-554-2291-8

Present affiliation: CEO at Novadex Pharmaceuticals AB

7. Studies on Nucleoside and Nucleotide Chemistry.
Tanmaya Pathak. ISBN 91-554-2288-8

Present affiliation: Professor of Chemistry, Indian Institute of Technology, Kharagpur, India
 

6. Studies on Nucleoside and Nucleotide Chemistry.
Agnes Nyilas. ISBN 91-554-2263-2

Present affiliation: Research Scientist, Szeged Institute of Biomolecular Science, Szeged, Hungary

5. Studies on Nucleoside Chemistry.
Herve Bazin. ISBN 91-554-2073-7

Present affiliation: Senior scientist at Cisbio Bioassays, France

1986

4. Studies on Nucleoside and Nucleotide Chemistry.
Christopher John Welch. ISBN 91-554-1902-X

Present affiliation: Research Director, Mase laboratories AB, Uppsala

1985

3. Studies on the Chemistry of Nucleosides and Nucleotides.
Jarmo Heikkilä. ISBN 91-554-1736-1

Present affiliation: Associate Professor, Helsinki University, Finland

1984

2. Studies on Oligoribonucleotide (RNA) Chemistry.
Marek Kwiatkowski. ISBN 91-554-1499-0

Present affiliation: Researcher, ICM, Structural and Molecular Biology program, Uppsala University, Uppsala

1982

1. Studies on Oligodeoxyribonucleotide (DNA) Chemistry.
Neil Balgobin. ISBN 91-7146-230-9

Present affiliation: Senior scientist, XenoDiagnostics, LLC Indianapolis

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